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KMID : 0614620100550060404
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Korean Journal of Gastroenterology
2010 Volume.55 No. 6 p.404 ~ p.409
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A Case of Cholangiocarcinoma Suspected by Continuous Elevation of CA 19-9 after Surgery of Xanthogranulomatous Cholecystitis
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Hwang Sang-Youn
Kim Joon-Suk
Jeong Ji-Bong
Kim Ji-Won
Kim Byeong-Gwan
Lee Kook-Lae
Ahn Young-Joon
Chang Mee-Soo
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Abstract
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Xanthogranulomatous cholecystitis (XGC) is an unusual and destructive inflammatory process that is characterized by thickening of the gallbladder (GB) wall with a tendency to adhere to neighboring organs. XGC is often mistaken for GB carcinoma, and the frequency of the coexistence of these two lesions is approximately 10%. Therefore, in case of severe XGC, there is chance of either overlooking the carcinoma or other significant lesions. CA 19-9 is commonly measured in the serum of patients with hepatobiliary malignancies. Although CA 19-9 can be elevated in benign conditions such as cholestasis, pancreatitis, tuberculosis, thyroid disease etc., malignancy should be considered at first in setting of its significant and persistent elevation. We report a case of a 62-year-old man who showed continuously rising level of CA19-9 over 2000 U/mL after cholecystectomy for xanthogranulomatous cholecystitis and finally was diagnosed as cholangiocarcinoma by short-term follow up.
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KEYWORD
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Cholecystitis, xanthogranulomatous, CA 19-9, Cholangiocarcinoma
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